•🧬SS-31 for research use only:
Optimize your project design with an advanced cell-permeable synthetic tetrapeptide reference standard. This high-purity chemical reagent incorporates a specialized alternating aromatic-cationic structural motif, providing academic laboratories with an unvarying tool developed to examine inner mitochondrial membrane behaviors and organelle localization cascades without baseline variability.
•⚙️1. Preclinical Handling & Stability
Thorough solid-phase automated synthesis delivers absolute batch uniformity and structural longevity across every unique reference container. To defend the target sequence chains from premature breakdown or cleavage, store the dry lyophilized powder tightly sealed inside freezer environments at -20°C, ensuring the vial stays fully protected from light and ambient moisture. Reconstitute the vacuum-sealed cake matrix smoothly using proper research-grade solvents under aseptic laboratory procedures, aliquoting working stocks to limit repeated freeze-thaw cycles. Move liquid portions immediately to refrigerator units at 2-8°C to maintain molecular integrity throughout the evaluation window. Secure domestic transport routes manage rapid same-day preparation on early orders to keep the material insulated during delivery.
•🔬2. Research Mechanisms & Preclinical FAQ
•📋Why does the presence of the dimethyltyrosine residue matter for analytical identity checks?
This compound incorporates a non-standard 2',6'-dimethyl-L-tyrosine residue alongside a D-arginine amino acid. These specific chemical modifications alter the theoretical molecular mass weight relative to conventional alignments, making mass spectrometry structural checks highly meaningful to confirm lot authenticity.
•📋How do researchers establish trace validation parameters before executing an assay layout?
Every unique synthesis lot connects directly to its authenticated Certificate of Analysis (COA). Independent testing networks verify a purity standard of at least 99 percent through reversed-phase high-performance liquid chromatography peak area integration, while mass spectrometry confirms molecular identity including the C-terminal amidation.
•📊3. Verified Sequence Specifications
| Compound Blueprint: | SS-31 Reference Standard (Aromatic-Cationic Tetrapeptide) |
| Synonyms / Identifiers: | Elamipretide / MTP-131 Sequence Alignment Reference |
| Technical Sequence: | D-Arg-Dmt-Lys-Phe-NH2 (Featuring C-Terminal Amidation) |
| Purity Certification: | ≥99% Analytical Purity Verified via UV RP-HPLC Testing |
| Physical Presentation: | Hygroscopic Lyophilized Compact Powder Cake Matrix |
| Application Intention: | Synthesized Chemical Supplier Reagent for In-Vitro Laboratory Use Only |
99% Purity Guaranteed
Independent Lab Tested
•🎓Preclinical & Scientific References
For verification of the biological mechanisms, mitochondrial membrane localization, and molecular traits cited in current biochemical essays, researchers are encouraged to review the official peer-reviewed literature and trials:
- • Szeto, H. H. (2006). Discovery and development of aromatic-cationic peptides as mitochondrial-targeted antioxidants. The AAPS Journal, 8(3), E521-E531.
- • Birk, A. V., et al. (2013). The cell-permeable tetrapeptide SS-31 binds to cardiolipin and alters inner mitochondrial membrane potential dynamics. Journal of Biological Chemistry, 288(32), 22847-22859.
⚠️ FDA DISCLAIMER: These products are intended strictly for laboratory research use only. They are not intended for human consumption, diagnostic, or therapeutic purposes. The statements on this website have not been evaluated by the Food and Drug Administration.
