•🧬STRUCTURAL EVALUATION: MT-2 (MELANOTAN II) VIAL for research use only

Comprehensive molecular profile and audited data regarding growth hormone secretagogue pathways.

•📋1. CORE PROFILE & MAIN SIGNALING

• Chemical Architecture: Supplied as a lyophilized reference material for in-vitro and preclinical laboratory work, structured as a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (alpha-MSH).
• Receptor Selectivity: Classified in literature as a non-selective melanocortin receptor agonist that engages several members of the receptor family, notably MC1R, MC3R, MC4R, and MC5R.
• Enzymatic Resistance: Its defining structural feature is a lactam bridge constraint that cyclizes the peptide backbone, holding the molecule in a conformation more resistant to enzymatic degradation than linear counterparts.

•📊2. VERIFIED SPECIFICATIONS MATRIX

• Chromatographic Resolution: High-Performance Liquid Chromatography (RP-HPLC) peak-area integration resolves the main peak from process-related impurities or uncyclized linear precursors, certifying purity thresholds ≥99%.
• Mass Spectrometry Data: Verifies definitive structural traits and molecular formula composition C50H69N15O9 matching target metrics via ESI-MS or MALDI-TOF testing.
• Traceability Mandate: Individual batches map directly to CAS number 121062-08-6 alongside standalone lot-specific certificates of analysis to support complete laboratory traceability.

•📋3. PRECLINICAL ASSAY ALIGNMENT

• Pathway Investigation: Frequently selected as a stable model ligand in receptor-pharmacology assays to observe how cell-based systems transduce signaling pathways.
• Transduction Assays: Utilized in preclinical investigations measuring cyclic AMP (cAMP) accumulation and radioligand-receptor binding profiles across cultured cell lines.
• Melanogenesis Studies: Cited as a reference tool compound in cultured melanocyte and melanoma cell models examining tyrosinase-related endpoints and pigment-pathway signaling.

•📊4. RECONSTITUTION & CLIMATE PROTOCOL

• Hygroscopic Preservation: Material is sensitive to temperature cycling; store freeze-dried powder strictly at -20°C, insulating the vial from light and moisture.
• Aseptic Reconstitution: Allow sealed vials to equilibrate smoothly to room temperature before opening to minimize condensation, then reconstitute with an appropriate research-grade solvent like bacteriostatic water under sterile techniques.
• Solution Oversight: Store reconstituted working stock solutions under continuous refrigeration at 2-8°C and protect from prolonged light exposure to defend baseline peptide sequence integrity.